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Leukopoiesis the formation of leukocytes or white blood cells. These blood cells are formed from haemopoietic stem cells pluripotensial derived from bone marrow. Haemopoietic stem cell berdifereniasi pluripotensial will be various types of committed stem cells, where the cells will form a dedicated erythrocytes and leukocytes major cell lineages, ie the beginning of myeloblasts myelocytic and lymphocytic starting from lymphoblasts (Shier et al. 2002).
White blood cells, especially granulocytes and monocytes formed and stored disumsum bone.
Leukopoiesis is the process of formation of leukocytes, which are stimulated by the presence of colony stimulating factors or colony stimulating factor. Stimulating (stimulants) colonies produced by white blood cells (leukocytes) adults. The development of any white blood cells begins with the division of stem cells into cell temopoitik "blast"
Myeloblasts which eventually evolved into granular leukocytes (granulocytes), namely eosinophils, neutrophils, and basophils.
Monoblas develop into monocytes.
Lymphoblasts will develop into lymphocytes. ?
"The formation and maturation of white blood cells"
Hematopoietic growth factors
Is a glycoprotein hormone that regulates the proliferation and differentiation of progenitor cells and mature cells function.
? Biological effects are mediated through specific receptors on target cells.
? There are various growth factors that have common characteristics.
? Work on the various stages of hematopoiesis
? Usually produced by several cell types
? It usually affects more than one cell line?
Granulocytes cell maturation
Maturation of granulocytes is divided into six stages:
Decreased cell bentul
Nuclear chromatin compaction
Changes in the cell layer core
The accumulation of cytoplasmic granules
Leukocytosis is WBC formation, occurs in Bone Marrow
Granulocytes and monocytes derived from myeloid stem cells, whereas limfocyte of lymphoid stem cells
Leukocytosis involves a series of mitosis and differentiation
Leukocytosis regulated by several growth factors and interleukin
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